产品名称：MMP-2
- 产品型号：兔单抗 IgG
- 产 地：美国
- 制 造 商：epitomics公司
- 产品规格：100ul
- 产品报价：$235美元 元(人民币) / PCS
- 关 注 度：559 次 [产品手册下载]
- 供 应 商：杭州华安生物技术有限公司
- 公司位于：浙江省 杭州市
- 备注:本信息仅针对企事业单位，不对个人用户适用
产品介绍
详细介绍：
Clone ID: Polyclonal
Antibody Type: Rabbit Polyclonal IgG Affinity Purified
Catalog#: 1842-1
Size: 100ul
Price: $ 235
Recommended Applications: WB, IHC, ICC, FC, IP
Species Reactivity: Human
Mol. Weight: 71 kDa
UniProt ID: P08253
Description: The matrix metalloproteinases （MMPs） are a family of closely related proteolytic enzymes which are involved in the degradation of different components of the extracellular matrix. There is increasing evidence to indicate that individual MMPs have an important role in tumor invasion and tumour spread. MMP2, also known as Gelatinase A, is a type IV collagenase that specifically cleaves type IV collagen, the major structural component of basement membranes. The metastatic potential of tumor cells has been found to correlate with the activity of this enzyme （1）. MMP2 is regulated differently from other MMPs, suggesting that it may play a unique role in cell-matrix interactions, including cell invasion. The conversion from the 72 kDa progelatinase A to the active 62 kDa species may be a key event in the acquisition of invasive potential（2）
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| Name: MMP-2 Rabbit Antibody PDF of Datasheet |
  |
Clone ID: Polyclonal
Antibody Type: Rabbit Polyclonal IgG Affinity Purified
Catalog#: 1842-1
Size: 100ul
Price: $ 235
Recommended Applications: WB, IHC, ICC, FC, IP
Species Reactivity: Human
Mol. Weight: 71 kDa
UniProt ID: P08253
Description: The matrix metalloproteinases （MMPs） are a family of closely related proteolytic enzymes which are involved in the degradation of different components of the extracellular matrix. There is increasing evidence to indicate that individual MMPs have an important role in tumor invasion and tumour spread. MMP2, also known as Gelatinase A, is a type IV collagenase that specifically cleaves type IV collagen, the major structural component of basement membranes. The metastatic potential of tumor cells has been found to correlate with the activity of this enzyme （1）. MMP2 is regulated differently from other MMPs, suggesting that it may play a unique role in cell-matrix interactions, including cell invasion. The conversion from the 72 kDa progelatinase A to the active 62 kDa species may be a key event in the acquisition of invasive potential（2）
Specificity: A synthetic peptide corresponding to residues near the C-terminus of human MMP2 was used as an immunogen.
Recommended Dilutions:
WB: 1:2000
IHC: 150 - 100
ICC: 1:50 – 100
Flow Cytometry: 1:20
IP: 1:50
Protocols for using Epitomics Rabbit Monoclonal Antibodies
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| A. Western blot analysis on A431 cell lysate using anti-MMP2 Rabbit Polyclonal antibody （cat. # 1842-1）, dilution 1:2000 | B. Immunohistochemical analysis of paraffin-embedded human breast carcinoma using anti-MMP2 Rabbit Polyclonal （cat. #1842-1）. |
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| C. Immunofluorescent staining of HeLa cells using anti-MMP2 Rabbit Polyclobal antibody （cat. #1842-1）. |
References:
| 1. | Murray GI, et al. J Pathol, 185（3）:256-61 |
| 2. | Yu, AE, et al. Biochem Cell Biol, 74（6）:823-31, 1996. |
点此查看供应商“杭州华安生物技术有限公司”联系方式
产品图片
![MMP-2[兔单抗 IgG]](/viewpic.htm?url=uploadfile/Image/2007-7/316185127171.jpg)
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