产品名称：M-CSF
- 产品型号：兔单抗 IgG
- 产 地：美国
- 制 造 商：epitomics公司
- 产品规格：100ul
- 产品报价：$235美元 元(人民币) / PCS
- 关 注 度：265 次 [产品手册下载]
- 供 应 商：杭州华安生物技术有限公司
- 公司位于：浙江省 杭州市
- 备注:本信息仅针对企事业单位，不对个人用户适用
产品介绍
详细介绍：
Clone ID: EP1179Y
Antibody Type: Rabbit Monoclonal IgG
Catalog#: 1876-1
Size: 100ul
Price: $ 235
Recommended Applications: WB, IHC, ICC, IP
Species Reactivity: Human
Mol. Weight: 19/37 kDa
UniProt ID: P09603
Description: Colony stimulating factor-1 （M-CSF） is a glycoprotein growth factor required for the proliferation and differentiation of mononuclear phagocytic cells. Findings indicate that M-CSF, under hormonal influence, plays a role in placental development and function and that steroid hormones may regulate developmental processes via their effects on the expression of tissue-specific growth factors （1）. M-CSF accelerates neointimal formation after vascular injury via the SDF-1-CXCR4 system, and the inhibition of this system has therapeutic potential for the treatment of cardiovascular diseases （2）. The immunosuppressor Sanglifehrin A inhibits M-CSF-dependent macrophage proliferation by arresting the G1 phase of the cell cycle but does not affect cell viability （3）. Several studies have demonstrated that CSFs are closely associated with tumor progression, metastasis and invasion through autocrine or paracrine mechanism in lung cancer （4）.
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| Name: M-CSF Rabbit Antibody PDF of Datasheet |
  |
Clone ID: EP1179Y
Antibody Type: Rabbit Monoclonal IgG
Catalog#: 1876-1
Size: 100ul
Price: $ 235
Recommended Applications: WB, IHC, ICC, IP
Species Reactivity: Human
Mol. Weight: 19/37 kDa
UniProt ID: P09603
Description: Colony stimulating factor-1 （M-CSF） is a glycoprotein growth factor required for the proliferation and differentiation of mononuclear phagocytic cells. Findings indicate that M-CSF, under hormonal influence, plays a role in placental development and function and that steroid hormones may regulate developmental processes via their effects on the expression of tissue-specific growth factors （1）. M-CSF accelerates neointimal formation after vascular injury via the SDF-1-CXCR4 system, and the inhibition of this system has therapeutic potential for the treatment of cardiovascular diseases （2）. The immunosuppressor Sanglifehrin A inhibits M-CSF-dependent macrophage proliferation by arresting the G1 phase of the cell cycle but does not affect cell viability （3）. Several studies have demonstrated that CSFs are closely associated with tumor progression, metastasis and invasion through autocrine or paracrine mechanism in lung cancer （4）.
Specificity: A synthetic peptide corresponding to residues on human M-CSF was used as an immunogen.
Recommended Dilutions:
WB: 1:50,000 （5 ng recombinant protein）
IHC: 1:50 – 100
ICC: 1:250 – 500
IP: 1:50
Protocols for using Epitomics Rabbit Monoclonal Antibodies
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| A. Western blot analysis on 5 ng of recombinant protein using anti-M-CSF RabMAb （cat. # 1876-1）, dilution 1:50,000. | B. Immunohistochemical staining of paraffin-embedded human tonsils using anti-M-CSF RabMAb （cat. #1876-1）. |
References:
| 1. | Pollard JW, et al. Nature 330（6147）:484-6, 1987. |
| 2. | Shiba Y, et al. Arterioscler Throm Vasc Biol, 27（2）:283- 9,006 |
| 3. | Sanchez-Tillo E, et al. Eur J Immunol. 36（9）:2515-24, 2006 |
| 4. | Uemura Y, et al. Int J Mol Med 18（2）:365-73, 2006. |
点此查看供应商“杭州华安生物技术有限公司”联系方式
产品图片
![M-CSF[兔单抗 IgG]](/viewpic.htm?url=uploadfile/Image/2007-7/314145867264.jpg)
客户留言(仅显示最新5条)
- 时间：2008-12-14 16:06:52用户：孙超客户信息反馈
你好，我买了你们公司的兔单抗M-CSF，我是检测人成骨细胞中M-CSF蛋白的表达水平，我已经做过4次了，换了很多条件，每次都是内参出来了，但是我要的M-CSF却没有出来，而且是一点也没有出来，我在怀疑是不是你们抗体的问题，请你们帮我分析一下，急、、、看到留言速回，谢谢
您好，非常抱歉给您带来这么多不便，请与周一与我们销售员联系，我们的直线是0571-88062880，0571-88062850，免费电话：4008-123-175. [回复于 2008-12-14 20:12:36]
![氧氟沙星（OFL）酶联免疫检测试剂盒（竞争法）[HuaM 006001]](/images/nopic.gif)
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